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分类
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Col1a2-DreERT2小鼠
分类: Cre鼠
发布时间: 2019-07-11 11:00
应用:骨骼肌系统
级别:SPF
类型:TG/KI
背景:C57BL/6
该Dre小鼠与Frox小鼠交配后,在Dre特异表达的组织或者器官或细胞中,两个Rox位点间的外显子或元件将被删除,达到条件性敲除或过表达的目的。
Dre-Rox重组系统与Cre-loxP系统类似,具有高效的位点特异性重组活性。可被重组酶Dre识别的DNA序列称为rox位点。
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