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内容编辑Sting1-I199N小鼠
分类: 免疫肿瘤鼠
发布时间: 2019-09-29 11:00
应用：干扰素
级别：SPF
类型：PM
背景：C57BL/6
名称：Sting1-I199N
编号：LM000153
级别：SPF
类型：PM
背景：C57BL/6
名称：Sting1-I199N
编号：LM000153
Tmem173 Goldenticket Sting
使用基因编缉技术使小鼠表达Goldenticket（Tmem173gt），Sting基因（Tmem173）的I199N错义突变等位基因。不产生IFN-β以响应循环二核苷酸或李斯特菌单核细胞增多性感染。可用于与细胞质病原体DNA的检测，先天免疫反应和肿瘤微环境的探索相关的研究。
| 疾病造模 | 代养代繁 | 药效评估 | 生化分析 | 行为分析 | 影像检测 | 病理检测 |
使用基因编缉技术使小鼠表达Goldenticket（Tmem173gt），Sting基因（Tmem173）的I199N错义突变等位基因。不产生IFN-β以响应循环二核苷酸或李斯特菌单核细胞增多性感染。可用于与细胞质病原体DNA的检测，先天免疫反应和肿瘤微环境的探索相关的研究。
| 疾病造模 | 代养代繁 | 药效评估 | 生化分析 | 行为分析 | 影像检测 | 病理检测 |