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分类
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Dlgap3敲除小鼠
分类: 神经退行性疾病鼠
发布时间: 2019-08-28 11:00
应用：强迫症
级别：SPF
类型：KO
背景：C57BL/6
名称：Dlgap3-KO
编号：LM000185
Sapap3
使用基因编缉技术删除Dlgap3基因外显子，建立Dlgap3敲除小鼠模型。行为和神经异常，具有人类强迫症（过度自我修饰，面部病变和焦虑行为）和皮质纹状体神经传递改变的特征，可能有面部皮肤病变。
| 疾病造模 | 代养代繁 | 药效评估 | 生化分析 | 行为分析 | 影像检测 | 病理检测 |
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