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内容编辑Kras-LSL-G12D小鼠
分类: 自发肿瘤鼠
发布时间: 2019-08-21 11:00
应用：肺癌
级别：SPF
类型：TG
背景：C57BL/6
名称：Kras-LSL-G12D
编号：LM000192
级别：SPF
类型：TG
背景：C57BL/6
名称：Kras-LSL-G12D
编号：LM000192
使用基因编缉技术使小鼠表达Kras-G12D突变序列，建立Kras-G12D突变小鼠模型。Kras转基因小鼠模型，携带点突变Kras-G12D，允许致癌蛋白表达，与组织特异性Cre鼠交配可获得非常高的肺部肿瘤频率。可用于研究肺癌的发生、发展及转移，及肺癌相关药物的筛选。c-K-ras，C+K转基因小鼠，肺癌小鼠模型。
| 疾病造模 | 代养代繁 | 药效评估 | 生化分析 | 行为分析 | 影像检测 | 病理检测 |