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F2rl1敲除小鼠
分类: 免疫炎症鼠
发布时间: 2019-07-28 11:00
应用:疼痛、哮喘、胰腺炎、炎症、瘙痒
级别:SPF
类型:KO
背景:C57BL/6
名称:F2rl1-KO
编号:LM000216
级别:SPF
类型:KO
背景:C57BL/6
名称:F2rl1-KO
编号:LM000216
Par2
使用基因编缉技术删除F2rl1基因exons,建立F2rl1基因敲除小鼠模型。蛋白酶活性受体2(F2R Like Trypsin Receptor 1,F2rl1,Protease-Activated Receptor 2,PAR2)是蛋白酶活化受体的成员之一,分布在许多组织和细胞中(如皮肤、呼吸道上皮细胞和胰腺等),具有广泛的生物学效应,参与疼痛、哮喘、胰腺炎、炎症和瘙痒等多种疾病的发生和形成。
| 疾病造模 | 代养代繁 | 药效评估 | 生化分析 | 行为分析 | 影像检测 | 病理检测 |
使用基因编缉技术删除F2rl1基因exons,建立F2rl1基因敲除小鼠模型。蛋白酶活性受体2(F2R Like Trypsin Receptor 1,F2rl1,Protease-Activated Receptor 2,PAR2)是蛋白酶活化受体的成员之一,分布在许多组织和细胞中(如皮肤、呼吸道上皮细胞和胰腺等),具有广泛的生物学效应,参与疼痛、哮喘、胰腺炎、炎症和瘙痒等多种疾病的发生和形成。
| 疾病造模 | 代养代繁 | 药效评估 | 生化分析 | 行为分析 | 影像检测 | 病理检测 |
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