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肝缺血(HI)小鼠模型
分类: 消化
发布时间: 2021-05-03 00:00
方法:缺血再灌注肝损伤
品系:SPF级Balb/c小鼠,雄性,周龄为6w-8w,体重为20g-25g。
类型:成品模型
名称:Mouse Model for Hepatic Ischemia (HI)
编号:LM80642
品系:SPF级Balb/c小鼠,雄性,周龄为6w-8w,体重为20g-25g。
类型:成品模型
名称:Mouse Model for Hepatic Ischemia (HI)
编号:LM80642
模型评价
模型评价
肝脏缺血损伤评分:
0分:无肝细胞损伤
1分:轻度损伤,特点为细胞质空泡化,病灶核固缩
2分:中度损伤,血窦膨胀,细胞溶质空泡化,细胞边界模糊
3分:中度到重度损伤,凝固性坏死,大量血窦膨胀,红细胞渗出到肝锁,嗜伊红细胞增多,中性白细胞着边(附着于血管壁)
4分:严重坏死,失去肝脏结构,肝索崩解,出血,嗜中性粒细胞渗入
模型评价
肝脏缺血损伤评分:
0分:无肝细胞损伤
1分:轻度损伤,特点为细胞质空泡化,病灶核固缩
2分:中度损伤,血窦膨胀,细胞溶质空泡化,细胞边界模糊
3分:中度到重度损伤,凝固性坏死,大量血窦膨胀,红细胞渗出到肝锁,嗜伊红细胞增多,中性白细胞着边(附着于血管壁)
4分:严重坏死,失去肝脏结构,肝索崩解,出血,嗜中性粒细胞渗入
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